
Diabetic ketoacidosis (DKA) is a serious condition that can lead to diabetic coma (passing out for a long time) or even death.
From the Intensive Care Unit of the Nepean Hospital Penrith NSW Australia: LINK: http://intensivecare.hsnet.nsw.gov.au/five/doc/education_packages/nepean/nepean_guide_DKA_2007.pdf
“Hyperglycaemic Emergencies derive from an absolute or relative insulin deficiency that leads to insufficient glucose uptake into the cells and concurrent breakdown of glycogen stores and new formation of glucose in the liver. Hyperglycaemic emergencies are life-threatening, and require immediate treatment in hospital, often with an admission to an intensive care unit (ICU)”
From The Royal Childrens Hospital, Melbourne:
“Diabetic ketoacidosis (DKA) is the combination of hyperglycemia, metabolic acidosis, and ketonaemia. It may be the first presentation for a child with previously undiagnosed diabetes.
All patients presenting with a blood glucose level (BGL) ≥ 11.1mmol/l should have blood ketones tested. If this test is positive (>0.6 mmol/l), assess for acidosis to determine further management. Urinalysis can be used for initial assessment if blood ketone testing is not available.
The biochemical criteria for DKA are:
- Venous pH < 7.3 or bicarbonate <15 mmol/l
- Presence of blood or urinary ketones
If ketones are negative, or the pH is normal in the presence of ketones, patients can be managed with subcutaneous (s.c.) insulin” LINK: http://www.rch.org.au/clinicalguide/guideline_index/Diabetes_Mellitus/
What is DKA? Simply….
When your cells don’t get the glucose they need for energy, your body begins to burn fat for energy, which produces ketones.
Ketones are acids that build up in the blood and appear in the urine when your body doesn’t have enough insulin. They are a warning sign that your diabetes is out of control or that you are getting sick.
High levels of ketones can poison the body. When levels get too high, you can develop DKA. DKA may happen to anyone with diabetes, though it is rare in people with type 2.
Treatment
Treatment for DKA usually takes place in the hospital. But you can help prevent it by learning the warning signs and checking your urine and blood regularly.
What are the Warning Signs of DKA?
DKA usually develops slowly. But when vomiting occurs, this life-threatening condition can develop in a few hours. Early symptoms include the following:
- Thirst or a very dry mouth
- Frequent urination
- High blood glucose (blood sugar) levels
- High levels of ketones in the urine
Then, other symptoms appear:
- Constantly feeling tired
- Dry or flushed skin
- Nausea, vomiting, or abdominal pain (Vomiting can be caused by many illnesses, not just ketoacidosis. If vomiting seek medical advice)
- Difficulty breathing
- Fruity odor on breath
- A hard time paying attention, or confusion
Ketoacidosis (DKA) is dangerous and serious
If you have any of the above symptoms, contact your health care provider IMMEDIATELY, or go to the nearest emergency room of your local hospital.
How Do I Check for Ketones?
Ideally you will be measuring your blood ketone level with strips similar to a blood testing strip. If unable to test you blood for ketones, test your urine.
Talk to your team and plan a sick day protocol: how often to test your blood for ketones if you are sick; when to go to hospital; etc.
Also, check for ketones when you have any symptoms of DKA.
What If I Find Higher-than-normal Levels of Ketones?
If your health care provider has not told you what levels of ketones are dangerous, then call when you find moderate amounts after more than one test. Often, your health care provider can tell you what to do over the phone. Sometimes this will help to keep you out of hospital. Sometimes it is the best thing to go to hospital. In any situation with ketones present, seek medical advice.
Call your health care provider at once if you experience the following conditions:
- Your ketone tests show high levels of ketones.
- Your ketone tests show high levels of ketones and your blood glucose level is high.
- Your ketone tests show high levels of ketones and you have vomited.
Do NOT exercise when you have ketones and your blood glucose is high. High levels of ketones and high blood glucose levels can mean your diabetes is out of control.
Be Pro-active: Have a ‘sick day plan’ prepared before you need it. It may also be helpful to have a family member or friend be aware of your sick day plan.
What Causes DKA?
Here are three basic reasons for moderate or large amounts of ketones:
- Not enough insulin Maybe you did not inject enough insulin. Or your body could need more insulin than usual because of illness.
- Not enough food When you’re sick, you often don’t feel like eating, sometimes resulting in high ketone levels. High levels may also occur when you miss a meal.
Hypo (low blood glucose) If testing shows high ketone levels in the morning, you may have had a hypo while asleep.
Hospital
Ideally, you will have a family member of friend with you who understands your diabetes well enough to be an advocate for you.
It may be an idea to have a small ‘hospital’ kit bag at home and at work. This bag can contain your plan for going to hospital: your sick day plan; names and numbers of support people; names and numbers of your usual health care team.
If you go to your local hospital with signs of keto-acidosis be prepared for health professionals who do not have a lot of experience with this situation. In hospitals there are a range of nurses and doctors: some with a good sound knowledge of diabetes, some with basic knowledge (and occasionally inaccurate knowldge) about diabetes.
Before you need it…
…make contact with your local hospital and request a copy of their DKA (Diabetic Keto-acidosis) policy / protocols.
Links to this type of document here:
http://www.chw.edu.au/about/policies/pdf/2008-8061.pdf
http://content.lib.utah.edu/utils/getfile/collection/ehsl-gradnu/id/74/filename/32.pdf
http://www.bimcmedicine.org/storage/files/pdfs/BIMC%20Adult%20DKA%20Protocol%202012.pdf

EMERGENCY ROOM
If you are familiar with the processes then you can ask for the staff looking after you when you arrive to follow their own hospital’s protocols.
It may be helpful to you also to take a printed copy and show the staff you have some knowledge of the correct thing to do.
On arriving at emergency ask these questions:
- Would you please measure my ketones and BGL? I have type 1 diabetes and I am trying to avoid an intensive care admission. Before I left home my ketone level was….. My health care team (if you have one, give the name of your endocrinologist) advised me to come to emergency when my ketone levels reached….. or, if I gave (for example) 2 or more extra doses of inuslin at home and still had ketones present
- Is it less expensive for the hospital to keep treat me here in emergency for a few hours than it is to end up sicker and in intensive care?
- Could you please ask one of the endocrine team to assess me.
- The names of the people who you see – and write them down.
- If you feel that you are not being treated appropriately, ask firstly for the person in charge – usually the nurse unit manager (or most senior nurse on duty). If you are still not satisfied, then the next step is to ask for the contact details of the ‘client liaison officer’ or similar person who your complaint/s can be directed to.
Your health is of prime importance in this situation, which, as mentioned above can be life threatening.
Stay Safe: Plan Ahead
Regards,
David, Diabetes Educator @ Diabetes Counselling Online
























